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per quanto riguarda Purtroppo vergognoso lsd1 inhibitor clinical trial scatola Cellula somatica Cuneo

LSD1 inhibition induces differentiation and cell death in Merkel cell  carcinoma | EMBO Molecular Medicine
LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma | EMBO Molecular Medicine

LSD1 activates a lethal prostate cancer gene network independently of its  demethylase function | PNAS
LSD1 activates a lethal prostate cancer gene network independently of its demethylase function | PNAS

Frontiers | A Phase 1 Proof of Concept Study Evaluating the Addition of an LSD1  Inhibitor to Nab-Paclitaxel in Advanced or Metastatic Breast Cancer  (EPI-PRIMED)
Frontiers | A Phase 1 Proof of Concept Study Evaluating the Addition of an LSD1 Inhibitor to Nab-Paclitaxel in Advanced or Metastatic Breast Cancer (EPI-PRIMED)

Figure 1 from Design, synthesis and biological activity of  3-oxoamino-benzenesulfonamides as selective and reversible LSD1 inhibitors.  | Semantic Scholar
Figure 1 from Design, synthesis and biological activity of 3-oxoamino-benzenesulfonamides as selective and reversible LSD1 inhibitors. | Semantic Scholar

EpiAxis Therapeutics clinical study validates targeting LSD1 inhibition
EpiAxis Therapeutics clinical study validates targeting LSD1 inhibition

Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid  leukemia cells for retinoic acid–induced differentiation | Science Advances
Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid–induced differentiation | Science Advances

LSD1 as a Biomarker and the Outcome of Its Inhibitors in the Clinical Trial:  The Therapy Opportunity in Tumor
LSD1 as a Biomarker and the Outcome of Its Inhibitors in the Clinical Trial: The Therapy Opportunity in Tumor

LSD1/KDM1A inhibitors in clinical trials: advances and prospects | Journal  of Hematology & Oncology | Full Text
LSD1/KDM1A inhibitors in clinical trials: advances and prospects | Journal of Hematology & Oncology | Full Text

New tranylcypromine derivatives containing sulfonamide motif as potent LSD1  inhibitors to target acute myeloid leukemia: Design, synthesis and  biological evaluation - ScienceDirect
New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation - ScienceDirect

Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces  Differentiation in Acute Myeloid Leukemia
Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia

Exploration of 5-cyano-6-phenylpyrimidin derivatives containing an  1,2,3-triazole moiety as potent FAD-based LSD1 inhibitors - ScienceDirect
Exploration of 5-cyano-6-phenylpyrimidin derivatives containing an 1,2,3-triazole moiety as potent FAD-based LSD1 inhibitors - ScienceDirect

Medicinal chemistry insights in the discovery of novel LSD1 inhibitors |  Epigenomics
Medicinal chemistry insights in the discovery of novel LSD1 inhibitors | Epigenomics

Summary of LSD1/KDM1A inhibitors in clinical trials and clinical use. a |  Download Table
Summary of LSD1/KDM1A inhibitors in clinical trials and clinical use. a | Download Table

Advances toward LSD1 inhibitors for cancer therapy | Future Medicinal  Chemistry
Advances toward LSD1 inhibitors for cancer therapy | Future Medicinal Chemistry

New tranylcypromine derivatives containing sulfonamide motif as potent LSD1  inhibitors to target acute myeloid leukemia: Design, synthesis and  biological evaluation - ScienceDirect
New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation - ScienceDirect

LSD1/KDM1A inhibitors in clinical trials: advances and prospects | Journal  of Hematology & Oncology | Full Text
LSD1/KDM1A inhibitors in clinical trials: advances and prospects | Journal of Hematology & Oncology | Full Text

Synergistic anti-AML effects of the LSD1 inhibitor T-3775440 and the  NEDD8-activating enzyme inhibitor pevonedistat via transdifferentiation and  DNA rereplication | Oncogenesis
Synergistic anti-AML effects of the LSD1 inhibitor T-3775440 and the NEDD8-activating enzyme inhibitor pevonedistat via transdifferentiation and DNA rereplication | Oncogenesis

Histone lysine specific demethylase 1 inhibitors - RSC Medicinal Chemistry  (RSC Publishing) DOI:10.1039/D0MD00141D
Histone lysine specific demethylase 1 inhibitors - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D0MD00141D

A proof of concept phase I/II pilot trial of LSD1 inhibition by  tranylcypromine combined with ATRA in refractory/relapsed AML patients not  eligible for intensive therapy | Leukemia
A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy | Leukemia

Summary of LSD1/KDM1A inhibitors in clinical trials and clinical use. a |  Download Table
Summary of LSD1/KDM1A inhibitors in clinical trials and clinical use. a | Download Table

Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and  histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell  lines | PLOS ONE
Small molecule inhibition of lysine-specific demethylase 1 (LSD1) and histone deacetylase (HDAC) alone and in combination in Ewing sarcoma cell lines | PLOS ONE

PDF] Advances toward LSD1 inhibitors for cancer therapy. | Semantic Scholar
PDF] Advances toward LSD1 inhibitors for cancer therapy. | Semantic Scholar

Advances toward LSD1 inhibitors for cancer therapy | Future Medicinal  Chemistry
Advances toward LSD1 inhibitors for cancer therapy | Future Medicinal Chemistry

Natural products as LSD1 inhibitors for cancer therapy - ScienceDirect
Natural products as LSD1 inhibitors for cancer therapy - ScienceDirect

LSD1 inhibitors in clinical trials. (A) Structure of TCP-based... |  Download Scientific Diagram
LSD1 inhibitors in clinical trials. (A) Structure of TCP-based... | Download Scientific Diagram

Molecules | Free Full-Text | Pharmacological Inhibition of LSD1 for Cancer  Treatment | HTML
Molecules | Free Full-Text | Pharmacological Inhibition of LSD1 for Cancer Treatment | HTML